Item – Theses Canada

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OCLC number
51446896
Link(s) to full text
LAC copy
LAC copy
Author
Moretti, Myla Emily,1971-
Title
Prospective follow-up of infants exposed to 5-aminosalicylic acid containing drugs through maternal milk.
Degree
M. Sc. -- University of Toronto, 1998
Publisher
Ottawa : National Library of Canada = Bibliothèque nationale du Canada, [2000]
Description
2 microfiches.
Notes
Includes bibliographical references.
Abstract
The aim of this prospective cohort study was to estimate the risk of the adverse effects in infants breastfed by mothers receiving 5-ASA-containing drugs while lactating. We conducted telephone interviews with 121 women exposed to the drugs while lactating and 121 controls. The mean age for the exposed infants at the time of follow-up was 22 $\pm$ 20 months while the mean age for the non-exposed infants at the time of follow-up was 21 $\pm$ 18 months. Most of the exposed group had been taking the medication long term at least throughout the pregnancy. Based on maternal reports there were 14 (12%) clinical events in the infants of the exposed group and 13 (11%) in the control group (p = 0.4). The profile of clinical events in the infants were similar in the two groups and often were explained by other causes. The results of this study suggest that 5-ASA-containing compounds do not pose a significant risk to breastfed infants.
ISBN
0612408450
9780612408456