Item – Theses Canada

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OCLC number
46508297
Author
Dunn, Edward J.(Edward Joseph),1956-
Title
Chemical modification of chitosan for microcapsule development and application in aquaculture.
Degree
M. Sc. -- Queen's University at Kingston, 1990
Publisher
Ottawa : National Library of Canada = Bibliothèque nationale du Canada, 1991.
Description
2 microfiches.
Notes
Includes bibliographical references.
Abstract
Chitosan ($\beta$-(1$\to$4)-2-amino-2-deoxy- scD-glucose) was chemically modified by alkylation with N-(2-bromoethyl) phthalimide, N-(3-bromopropyl)phthalimide, and N-(4-bromobutyl)phthalimide under slightly alkaline conditions in a water/acetone mixture at 25$\sp\circ$C. The resulting N-(phthalidimidoalkyl)chitosans were treated with hydrazine to remove the phthalidimido group resulting in the final N-(aminoalkyl)chitosan products. In a similar procedure polyvinyl alcohol (PVA) was alkylated with N-(3-bromopropyl)phthalimide then treated with hydrazine to give the N-(3-aminopropyl)PVA product. The above synthetic polymer derivatives, as well as chitosan, polyallyl amine, and polyethylenimine, were used to form membrane coatings around calcium alginate beads in which blue dextrans were entrapped. The microcapsules which formed were washed with distilled water and dehydrated with acetone. Elution of the blue dextran from the capsules in a buffered solution of pH 6 was followed spectrophotometrically. (Abstract shortened by UMI.)
ISBN
0315615532
9780315615533