Item – Theses Canada

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OCLC number
1017550666
Link(s) to full text
LAC copy
Author
Benayoun, Serge,1973-
Title
The impact of combined inhaled bronchodilator therapy in the treatment of COPD.
Degree
M. Sc. -- McGill University, 1999
Publisher
Ottawa : National Library of Canada = Bibliothèque nationale du Canada, [2001]
Description
1 microfiche
Notes
Includes bibliographical references.
Abstract
The introduction of a single inhaler comprising a [beta]2-agonist and ipratropiurn (Combivent®) in the treatment of Chronic Obstructive Pulmonary Disease (COPD) should enhance compliance, improve patient outcomes and result in lower medication costs. Using the Saskatchewan Health databases, a cohort of subjects initiating treatment with Combivent® was identified and followed up to one year. A reference cohort was formed from all subjects who were dispensed, for the first time, two canisters, one of ipratropium and one of inhaled [beta] 2-agonist, on the same day. Combivent® users presented lower costs associated with inhaled bronchodilators (RR = 0.83; 95% Cl: 0.76 - 0.92), despite a slight increase in overall use of these medications (RR = 1.16; 95% Cl: 1.07 - 1.26). Moreover, the use of other respiratory drugs and antibiotics was unchanged (RR = 1.03; 95% Cl: 0.93 - 1.16). The availability of a simpler dosing regimen did not alter significantly the treatment of COPD and resulted in appreciable cost savings.
ISBN
0612507203
9780612507203